Showing posts with label Completed project. Show all posts
Showing posts with label Completed project. Show all posts

Review of methods & challenges in cost-effectiveness of genomics



The overall project aim is to establish appropriate methods to assess the cost effectiveness of genetic services in the NHS. This first piece of work will undertake a literature review on the methods used to undertake economic evaluation of genetic services. This piece of work will be used to establish what understanding already exists regarding the methods of economic evaluation as applied to genetic services and to identify any specific methods challenges to the full economic evaluation of genetic services which warrant further research.

Project team: Laura Bojke, Eldon Spackman, Mark Sculpher.

Contact: Eldon Spackman. Click here to email Eldon

Value based Pricing - Elicitation of societal preferences

This project focused on elicitation of societal preferences to establish whether society is willing to pay a premium for drugs to treat diseases that inflict high burden of illness and for drugs that offer high QALY gains. An online survey of over 6,000 respondents was carried out and the results were used to generate weights through econometric modelling. It was an innovative piece of work designed to provide policy-relevant results. It is not yet clear how these results will be used by DH in 2014 when VBP comes into force. Sheffield and York Universities assessed the impact of the proposed methodology to investigate the impacts of possible weightings by applying them to models submitted to NICE.

Project team: John Brazier, Donna Rowen, Clara Mukuria, Sophie Whyte, Anju Keetharuth, Aki Tsuchiya, Roberta Ara, Arne Risa Hole, Angela Robinson, Phil Shackley

Contact: John Brazier. Click here to email John

Modelling the cost-effectiveness of early awareness interventions for the early detection of colorectal cancer

Contact

Sophie Whyte. Click here to email Sophie

Review of methodological quality of cost-effectiveness evaluations of radiotherapy for breat, colorectal, prostate, cervical and head and neck cancer

Output

Barbieri M. et al. What   is the quality of economic evaluations of non-drug therapies? A systematic review of economic evaluations of radiotherapy for cancer.

Contact

Roberta Ara. Click here to email Roberta

Review of methodological quality of cost-effectiveness evaluations of surgical interventions for breast, colorectal or prostate cancer

Output

Ara R, et al. Are policy decisions on surgical procedures in cancer informed by robust economic evidence? A systematic review of economic evidence of surgical interventions for breast, colorectal or prostate cancer.

Contact

Roberta Ara. Click here to email Roberta

Methods to assess the cost-effectiveness of individualised care

This project includes an assessment of the different dimensions of heterogeneity affecting the cost effectiveness of health and care interventions and the value of identifying sub-groups (i.e. tailoring care to individuals in whom it is most cost effective). It also considers how patient choice feeds can be used to individualise care within a resource constrained health system.

Outputs

Espinoza M, Manca A, Claxton K, Sculpher M. The value of heterogeneity for cost-effectiveness subgroup analysis: conceptual framework and application. Forthcoming.

Presentations

Sculpher M. Economics Agenda for Development of Effective Personalized Medicine Strategies: Value of information. Symposium entitled 'Creating a Personalized Medicine Paradigm for Oncology', CRP-Santé, Luxembourg,18-19 June 2012

Project team

Manuel Espinoza, Mark Sculpher, Karl Claxton, Andrea Manca

Contact